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We seek a PhD candidate who is passionate about energy and sustainability scientific problems with a focus on the critical material perspective. Successful candidate will be under supervision of Prof. Xin Sun, working with colleagues at the Integrated Research on Energy, Environment and Society group (IREES - https://www.rug.nl/research/irees/?lang=en), within Energy and Sustainability Research Institute Groningen (ESRIG).Although the clean energy technologies (e.g., solar & wind power, electric vehicles) are preferable from a decarbonization perspective, their deployment causes a surging demand of critical materials, with increasing concern of their high supply concentration, negative environmental and social impacts, by-product issues, geopolitical instability, and other unsustainable factors. There is a pressing need to tackle the challenge of coordinating the economic, environmental, and social impacts of energy-climate-material nexus.In this context, the proposed PhD project focuses on the demand management solutions to mitigate the critical material impacts of the energy transition. Potential topics include (1) modeling dynamic demand for critical materials in multiple energy decarbonization and transportation electrification scenarios; (2) identifying the primary technological and societal factors that drive changes in demand patterns for critical materials; and (3) developing integrated approaches that simultaneously satisfy energy and mobility requirements while minimizing the need for critical materials and their environmental footprints. This project would involve with methodologies of dynamic material flow analysis, life cycle assessment, integrated assessment model, system dynamics, big data analysis, and design of new approaches for specific themes.The PhD learning experience includes multidisciplinary data analysis, modeling and empirical research, along with soft skills including teamwork research, high-impact writing, visual & oral presentation, networking, and career development.Founded in 1614, the University of Groningen enjoys an international reputation as a dynamic and innovative institution of higher education offering high-quality teaching and research. Flexible study programmes and academic career opportunities in a wide variety of disciplines encourage the 34,000 students and researchers alike to develop their own individual talents. As one of the best research universities in Europe, the University of Groningen has joined forces with other top universities and networks worldwide to become a truly global centre of knowledge.The Faculty of Science and Engineering (FSE) is the largest faculty within the University. We offer first-rate education and research in a wide range of science and engineering subject areas, from mathematics, astronomy and mechanical engineering, to interdisciplinary fields such as artificial intelligence, pharmacy and nanoscience. Our community has an open and informal character with students and staff from around the world.Requirements: We expect you to have:• a MSc degree in Science or Engineering discipline, preferably Environmental, Geographical, Geological, Energy, Chemical, Mechanical, and Earth System• proficiency in both writing and oral presentation skills in English• strong team player who works efficiently both independently and collaboratively• general data collection, modeling and analytics, and programming skills (R/Python/Matlab), knowledge of artificial intelligence methods is a plus• desirable theoretical and practical expertise in research about critical material, energy transition, climate change or other relevant topics, exemplified by a notable academic track record• passion for scientific questions and interest in interdisciplinary subjects• ability to think critically and systematically.Salary Benefits: We offer you, following the Collective Labour Agreement for Dutch Universities:• a salary of € 2,770 gross per month in the first year, up to a maximum of € 3,539 gross per month in the fourth and final year for a full-time working week• a full-time position (1.0 FTE)• a holiday allowance of 8% gross annual income• an 8.3% end-of-the-year allowance• a position for four years; first, you will get a temporary position of one year with the option of renewal for another three years; prolongation of the contract is contingent on sufficient progress in the first year to indicate that successful completion of the PhD thesis within the contract period is to be expected. A PhD training program is part of the agreement, and you will be enrolled in the Graduate School of the Faculty of Science and Engineering.Starting date is negotiable and preferably not later than December 2024.Work Hours: 38 hours per weekAddress: Broerstraat 5

We have an opening for an Assistant Professor to strengthen our position in the field of Science, Technology, Engineering, and Mathematics (STEM) higher education. STEM education is primarily concerned with the theories, tools, methods, and approaches that facilitate the practice of STEM or the study of STEM through an interdisciplinary approach. As such, the field engages with questions related to STEM literacy, STEM thinking, problem-solving, critical thinking, teaching and learning, as well as connections between the STEM disciplines.We offer you a full-time position and excellent career opportunities in our faculty’s career system Career Paths in Science and Engineering, including the perspective to get a permanent appointment (tenure) in 1-3 years and become Full Professor in approximately 10 years.As Assistant Professor with a focus on research you will:- play a significant role in the development of research and education at the Faculty of Science and Engineering, both at the course and the program level, in the area of STEM education- set up and develop your own research line and research group as part of the Institute for Science Education and Communication- supervise PhD students in the Institute for Science Education and Communication- acquire external funding- promote the societal relevance of your research- contribute to the organization of the faculty, for example by participating in working groups and committees- teach an introductory course in one of the undergraduate programs of the Faculty of Science and Engineering- supervise scientific research projects in STEM education for the students in the master’s program Science Education and Communication- teach the master’s level course “Research Methods in Education” - contribute constructively to interdisciplinary collaboration in Science, Technology, Engineering and Mathematics (STEM) education at the Institute and Faculty levels- participate actively in international research networks.At the stage of Assistant Professor, 60% of your time is dedicated to research, 30% to teaching and education development, and 10% to organizational tasks.OrganisationThe University of Groningen is a research university with a global outlook, deeply rooted in Groningen, City of Talent. Groningen is the lively capital of the Northern Netherlands with a high quality of life and affordable living conditions. The University has 37000 students in BSc and MSc programmes, 4400 PhD students, and 4600 staff members. Our students and staff come from all around the world.Quality has been our top priority for over four hundred years, and with success. The University is currently in or around the top 100 on several influential ranking lists. The Faculty of Science and Engineering (FSE) is the largest faculty within the University. We offer first-rate education and research in a wide range of science and engineering disciplines, from classical disciplines such as mathematics, astronomy and mechanical engineering, to interdisciplinary fields such as artificial intelligence, pharmacy and nanoscience. At FSE, education and research are strongly intertwined, and we value a strong disciplinary basis for our students. Our programmes in science and engineering, while diverse, share a common view on best practices for research-driven, international education. We are proud of the open, inclusive, and informal character of our community.The position we offer will be embedded in the Centre for Learning and Teaching which aims to improve Science, Technology, Engineering, and Mathematics (STEM) education at the university level through research. This is done through explorative and intervention-based studies that include the development, implementation, and impact evaluation of curriculum materials, course design, pedagogical tools and instructional strategies as well as the use of digital tools in teaching and learning.The Centre for Learning and Teaching works closely with the Science Shop, Science LinX, research schools (e.g. Aletta Jacobs School of Public Health) institutes and units (e.g. Teacher Education, Professionalisation and Innovation of Education, Science and Society, Diversity, Equity and Inclusion) at the University of Groningen and it is affiliated with international organizations and associations (e.g., European Society for Research in Mathematics Education, Young European Researchers in Mathematics Education, International Group for the Psychology of Mathematics Education, European Science Education Research Association, National Association of Research in Science Teaching).The two-year MSc-programme Science Education and Communication caters to students with a BSc in science, mathematics or engineering, and trains them to become either a science teacher in high school or a professional in the broad field of science communication.Requirements: We seek candidates with the following qualifications and skills: - a PhD degree in STEM Education or a related field (e.g. Science Education, Mathematics education, Biology Education, Artificial Intelligence in Education) with a focus on higher education - excellent research skills in research methodologies relevant for studying STEM learning and teaching in higher education: quantitative and/or qualitative research methods, practice-based research, participatory action research, or ethnography- excellent research qualities, as shown by a publication record in international peer-reviewed journals and proceedings of renowned conferences and a research statement- a great affinity with and a good track record in teaching, appropriate for the career stage- preferably at least two years of postdoctoral experience outside of the Netherlands- a relevant international network- the potential to acquire substantial research grants from external sources- demonstrable communicative and organizational competences- the ambition and the potential to develop academically- the ability to work well with others in international and diverse teams- good command of spoken and written English.Furthermore, we expect all new staff members to either have a University Teaching Qualification (Dutch: Basiskwalificatie Onderwijs) or obtain it within 3 years and, if they do not already speak it, to learn the Dutch language within at most five years. Salary Benefits: The Faculty of Science and Engineering of the University of Groningen was the first on the European mainland to introduce a tenure track career policy, 20 years ago, and with significant success. We have attracted great talents that have contributed strongly to the worldwide leading position of our faculty’s ten research institutes. Our career system has helped our staff members to develop highly successful and rewarding academic careers. The latest version of this system, ‘Career Paths in Science and Engineering’, offers:- diverse career paths with a focus on research, education or impact - dynamic career paths, in which staff members can switch focus in the course of their career- promotion to Assistant Professor level 1, in combination with a permanent contract, already after 1 - 3 years, provided the relevant criteria are met - promotion to Associate Professor after 5 years, and promotion to Full Professor after another 5 years, if the corresponding criteria are met- significant freedom for staff members whether and when to apply for promotion.For more information about Career Paths in Science and Engineering, see: https://www.rug.nl/fse/meet-the-faculty/vacatures/vacatures/careerpaths/. Please consider the career path with a focus on research for the criteria for tenure and for promotion to more senior position.As starting conditions, we offer a salary, depending on qualifications and work experience, from € 4,332 up to a maximum of € 6,737 gross per month (scale 11 or 12 CAO Dutch Universities, depending on your career stage) for a full-time position as Assistant Professor. Additionally, we offer:- a holiday allowance and an end-of-year bonus of respectively 8% and 8.3% of your yearly salary- a pension scheme- maternity and parental leave- the possibility of working part-time (0.9 FTE or 0.8 FTE)- a mentor programme and a broad range of opportunities for personal development- dual career support for partners of new faculty members moving to Groningen.Consider our website for more information about the working conditions at the University of Groningen: https://www.rug.nl/about-ug/work-with-usWork Hours: 38 hours per weekAddress: Broerstraat 5

We are looking for two highly motivated and enthusiastic PhD candidates with a strong background in microbiology, bioengineering, bioinformatics or closely related fields to join the Systems Biology of Predatory Bacteria group of Dr Renske van Raaphorst.The bacterial predator Bdellovibrio bacteriovorus has an unusual life cycle. When the fast-swimming predator encounters a prey bacterium, it attaches to the prey and enters the periplasm. There, B. bacteriovorus grows into a large filament while digesting the prey content, finally dividing into a variable number of daughter cells, leaving only prey debris behind.B. bacteriovorus can kill a wide range of Gram-negative bacteria, including E. coli, Salmonella, Vibrio cholerae and Pseudomonas spp., making it especially interesting to find out how it recognizes, invades, kills & digests its prey. In the last years, technical advances have been made by different research groups, making it possible to genetically modify this bacterium and track its growth cycle using time-lapse microscopy. However, though several genes important for prey invasion were identified, most of the B. bacteriovorus predatory cycle remains elusive.Our group uses systems approaches to identify genes that are essential for B. bacteriovorus predation and growth. We do this using state-of-the-art screening approaches such as transposon-sequencing (tn-seq). The resulting screening libraries will be further investigated using a combination of quantitative fluorescence microscopy and advanced image analysis. As B. bacteriovorus is an atypical bacterium, we often use creative approaches to develop new experimental setups and analysis methods.The Systems Biology of Predatory Bacteria group is embedded in the Molecular Microbiology unit at the Groningen Biomolecular Sciences and Biotechnology Institute, which provides an inspiring, interdisciplinary and collaborative research environment. The PhD candidates will further receive excellent training through innovative research projects, advanced courses and training opportunities, complemented by workshops on research, transferable skills and teaching. As a PhD candidate, you are committed to conduct independent and original scientific research, to report on this research in international publications and presentations, and to present the results of the research in a PhD dissertation, to be completed within 4 years.OrganisationFounded in 1614, the University of Groningen enjoys an international reputation as a dynamic and innovative centre of higher education offering high-quality teaching and research. Flexible study programmes and academic career opportunities in a wide variety of disciplines encourage the 34,000 students and researchers alike to develop their own individual talents. As one of the best research universities in Europe, the University of Groningen has joined forces with other top universities and networks worldwide to become a truly global centre of knowledge.The Groningen Biomolecular Sciences and Biotechnology Institute (GBB - http://www.rug.nl/gbb), one of the larger institutes of the Faculty of Science and Engineering (FSE), provides an excellent environment for top-notch research in the field of biomolecular sciences. Thirteen vibrant research units with strong roots in biochemistry, biophysical chemistry, cell biology, computational biology, genetics, microbiology, molecular biology, and systems biology are organized in two focal areas: ‘Molecular Mechanisms of Biological Processes’ and ‘Physiology and Systems Biology’.Requirements: The successful applicant has:• a Master's degree with specialization in microbiology, bioengineering, bioinformatics or related topics (if not graduated yet, please indicate the expected graduation date)• research experience in biochemistry, microbiology or related topics• a creative, open mind and good English skills• excellent interpersonal skills combined with an ability to work efficiently both independently and in a team.Experience in genetic engineering of bacteria, microscopy or statistics is of advantage.Salary Benefits: We offer you following the Collective Labour Agreement for Dutch Universities:• a salary of € 2,770 gross per month in the first year, up to a maximum of € 3,539 gross per month in the fourth and final year• a full-time position (1.0 FTE)• a holiday allowance of 8% of gross annual income• an 8.3% end-of-the-year allowance.The successful candidates will first be offered a temporary position of one year with the option of renewal for another three years. Prolongation of the contract is contingent on sufficient progress in the first year to indicate that successful completion of the PhD thesis within the next three years is to be expected. A PhD training program is part of the agreement and the successful candidate will be enrolled in the Graduate School of Science and Engineering.The conditions of employment: https://www.rug.nl/about-us/work-with-us/The planned starting date is August/September 2024, however, there is some flexibility in the starting date.Work Hours: 38 hours per weekAddress: Broerstraat 5

Applications are invited for one 4-year PhD study, in the research group of Dr F. Bianchi part of the Molecular Immunology group (Groningen Biomolecular Sciences and Biotechnology Institute - http://www.rug.nl/gbb). The PhD study entails a close collaboration with Dr J.R. Prins part of the reproductive immunology group at the University Medical Centre Groningen. The successful applicant will work on a multidisciplinary project aimed at developing a prognostic test for Preeclampsia.During pregnancy, the maternal immune system adapts to tolerate the fetus. Insufficient tolerance is linked to preeclampsia, an inflammatory condition affecting 5-10% of pregnancies, leading to maternal and neonatal mortality and morbidity. Preeclampsia is often diagnosed late, usually resorting to early delivery with frequently detrimental consequences for the fetus.Early prediction of preeclampsia is hard due to the absence of clear symptoms and lack of reliable early biomarkers for disbalances in the T-cell populations. To address this, this project aims to create a robust prognostic test. This test will quantitatively measure the maternal inflammatory response to paternal Major Histocompatibility Complex (MHC) molecules early in pregnancy due to T-cell disbalances, which together with the T cell fitness is a predictor for complicated pregnancy such as preeclampsia.Particularly, the candidate will:• determine maternal T cell responses against isolated fetal / paternal MHC molecules• identify abnormal expression of immune checkpoints in T-regs and T-effs from peripheral blood of preeclamptic women as candidate prognostic markers• determine combined prognostic value of checkpoint markers and MHC probes in preeclampsia.PhD candidates will receive excellent training through cutting-edge research projects, advanced courses and training opportunities, complemented by workshops on generic research, transferable skills and teaching. As a PhD candidate, you are committed to conduct independent and original scientific research, to report on this research in international publications and presentations, and to present the results of the research in a PhD dissertation, to be completed within 4 years. PhD candidates are expected to contribute 10% of their overall workload to teaching.HTRICThis project is supported by and part of the Health Technology Research and Innovation Cluster (HTRIC). The Health Technology Research and Innovation Cluster is rethinking the future of healthcare. We bring academic research, health technology, and clinical practice together to tackle the challenges faced by today’s healthcare system. Our aspiration? More healthy years of life for the people around us!Through our research, we will foster new developments that support healthy aging and longevity while improving people’s quality of life and making healthcare more efficient. We focus on the entire innovation chain, from societal and clinical demands to groundbreaking innovations and first-in-human applications.We aim to speed up innovation through the interplay of knowledge development, health technology development, and business development. By linking researchers, businesses, and external professionals, we want to develop technologies that will continue to improve and transform our healthcare system. This is what HTRIC stands for.OrganisationFounded in 1614, the University of Groningen (http://www.rug.nl) enjoys an international reputation as a dynamic and innovative center of higher education offering high-quality teaching and research. Flexible study programmes and academic career opportunities in a wide variety of disciplines encourage the 36,000 students and researchers alike to develop their own individual talents. As one of the best research universities in Europe, the University of Groningen has joined forces with other top universities and networks worldwide to become a truly global center of knowledge.This is a collaborative project between the Department of Molecular Immunology at the Faculty of Science and Engineering (FSE), and the Department of Obstetrics at the University Medical Center Groningen (UMCG - http://www.umcg.nl).City of Groningen: http://www.rug.nl/(...)/discover-groningen/Requirements: As this project involves basic and translational research in both biochemistry and Immunology, the ideal candidate has a strong multidisciplinary interest. Specifically, you must be able to acquire a solid knowledge of the immunological background and biochemistry techniques and have excellent communication skills to discuss and coordinate the collection of samples at the Obstetric department of the UMCG.Required:• MSc degree in the field of life sciences (Medicine, biomedical sciences, molecular biology, biochemistry, or related disciplines)• laboratory experience, for example with Immunology or experimental molecular biology research• excellent command of English language with strong communication skills• ability to work efficiently, independently as well as in a team• excellent communication skills.Preferred:• experience with mammalian cell culture, ELISA, flow cytometry and protein isolation/purification.Salary Benefits: We offer you, in accordance with the Collective Labour Agreement for Dutch Universities:• a salary of € 2,770 gross per month in the first year, up to a maximum of € 3,539 gross per month in the fourth and final year• a full-time position (1.0 FTE)• a holiday allowance of 8% gross annual income• an 8.3% end-of-the-year allowance.The successful candidate will first be offered a temporary full-time position (1.0 FTE) of one year with the option of renewal for another three years. Prolongation of the contract is contingent on sufficient progress in the first year to indicate that a successful completion of the PhD thesis within the next three years is to be expected. A PhD training programme is part of the agreement and the successful candidate will be enrolled in the Graduate School of Science and Engineering.The conditions of employment: https://www.rug.nl/about-us/work-with-us/The preferred starting date is 1 September 2024Work Hours: 38 hours per weekAddress: Broerstraat 5

We are seeking candidates with a Ph.D. in STEM education or related field; a background in any of the STEM disciplines or education and a strong interest in gender inclusivity framed in queer theory, professional development training, and mixed-methods research approached. The physical work location for this position will be Groningen, The Netherlands at the Zernike Institute for Advanced Materials. This position is a collaborative project between Zernike Institute for Advanced Materials (ZIAM) and the Centre for Learning and Teaching (CLT) at the University of Groningen.This postdoctoral position is part of the Erasmus+ Programme 'Partnerships for Innovation - Forward Looking Projects', which involves a consortium of ten partners, both universities and NGOs in Europe. Forward-Looking Projects are large-scale projects that have the potential of becoming mainstream and giving input for improving education, training, and youth systems, as well as bringing a substantial innovative effect in terms of methods and practices.The objectives of the project are to: 1. Develop a framework for gender and sexual diversity-inclusive STEM education2. Develop a training toolkit for gender and sexual diversity-inclusive STEM education3. Carry out professional development workshops for school teachers and university instructors OrganisationFounded in 1614, the University of Groningen enjoys an excellent international reputation as a dynamic and innovative institution of higher education offering high-quality teaching and research. Flexible study programmes and academic career opportunities in a wide variety of disciplines encourage the 34,000 students and researchers alike to develop their talents. As one of the best research institutions in Europe, the University of Groningen has joined forces with other top universities and networks worldwide to become a truly global centre of knowledge, situated in the vibrant city of Groningen in the north of The Netherlands.The Centre for Learning and Teaching aims to improve Science, Technology, Engineering, and Mathematics (STEM) education at the university level through research and professional development. This is done through explorative and intervention-based studies that include the development, implementation, and impact evaluation of curriculum materials, course design, pedagogical tools, and instructional strategies as well as the use of digital tools in teaching and learning.Requirements: The successful candidate for this position will have the following qualifications/qualities:- a PhD degree in STEM education or a related field- strong interest in gender and sexual diversity-inclusive STEM education- teaching experience at any level- demonstrably excellent skills in research methodologies relevant to studying learning and teaching: quantitative and/or qualitative research methods, practice-based research, participatory action research, or ethnography- a good track record in research, as shown by publications in international peer-reviewed journals - demonstrable organizational competences- excellent command of spoken and written English- very good communication skills, so as to function as an excellent team player in this collaborative effort- enthusiasm and initiative to perform creative research in an interdisciplinary setting.Salary Benefits: The University of Groningen offers, in accordance with the Collective Labour Agreement for Dutch Universities:- a salary of € 3,877 gross per month (scale 10, step 4) in the first year to a maximum of € 4,185 gross per month (scale 10, step 6) (salary scale Dutch Universities), based on a full-time position (1.0 FTE) depending of relevant work experience after attaining PhD- a gross holiday allowance of 8%- a gross 8.3% year-end bonus- a position for 15 months.Work Hours: 38 hours per weekAddress: Broerstraat 5

Intestinal fibrosis is a common complication in chronic inflammatory bowel diseases (IBD) like Crohn’s Disease and ulcerative colitis. It is a serious therapeutic problem, which is difficult to diagnose and treat. Intestinal tissue is easy to access with nanoparticles, which offers excellent opportunities for therapy and diagnosis e.g. a theranostic approach.The current proposal aims to find (I) relevant target receptors in diseased intestinal tissue, with special focus on macrophages and fibroblasts, (II) prepare lipid nanoparticles that bind to these receptors enabling delivery of fluorescence labels and experimental drugs into the target cells, and finally (III) test the application of these constructs to monitor disease activity and effects of drugs. Research will be performed in cultures of fibroblasts and precision-cut intestinal slices from IBD patients. The aim is to image fibroblast and macrophage accumulation, and explore the effectivity of a cell-specific therapeutic approach. OrganizationThe vacancy is within the groups of Prof. Dr. Klaas Poelstra and Prof. Dr. Peter Olinga at the Groningen Research Institute of Pharmacy, Faculty of Science and Engineering, University of Groningen and Prof. dr. Klaas Nico Faber, University Medical Center Groningen. The research project aims at developing innovative cell-selective delivery strategies for nanoparticles to fibroblasts and macrophages for the imaging and treatment of intestinal fibrosis associated with Inflammatory Bowel Diseases.The University of Groningen (founded in 1614) has a long tradition of academic excellence, being one of the oldest research universities in Europe. The University is currently in or around the top 100 on several influential ranking lists. Currently approximately 30,000 students are enrolled and about 1,500 PhD students work on their theses. The city of Groningen is a historic town and among the ten biggest cities in The Netherlands. It is a vibrant student town with a direct train connection to Schiphol Airport near Amsterdam.The project is awarded by The Health Technology Research and Innovation Cluster (HTRIC). HTRIC is rethinking the future of healthcare. We bring academic research, health technology, and clinical practice together to tackle the challenges faced by today’s healthcare system. Our aspiration? More healthy years of life for the people around us!Through our research, we will foster new developments that support healthy aging and longevity while improving people’s quality of life and making healthcare more efficient. We focus on the entire innovation chain, from societal and clinical demands to groundbreaking innovations and first-in-human applications.We aim to speed up innovation through the interplay of knowledge development, health technology development, and business development. By linking researchers, businesses, and external professionals, we want to develop technologies that will continue to improve and transform our healthcare system. This is what HTRIC stands for.The Groningen Research Institute of Pharmacy (GRIP) is part of the Faculty of Science and Engineering (FSE) of the University of Groningen and collaborates closely with the University Medical Center Groningen (UMCG). The pharmaceutical and medical research within GRIP and the UMCG is very multidisciplinary. This project bridges the gap between clinical and biomedical sciences on the one hand and drug design and development on the other hand. The interaction between Pharmaceutical Sciences and the UMCG offers excellent opportunities for groundbreaking research. In particular, the research on Nanomedicines is at the cutting edge between these disciplines.Requirements: We are looking for an enthusiastic and talented PhD candidate with- a MSc degree in Medical Biology, Pharmacy, Pharmaceutical Sciences or a related field- research experience in the field of molecular biology, preferably with experience in qPCR, western blotting, FACS, immunohistochemistry and/or mammalian cell cultures- capacity to think analytically and creatively- high motivation- ability to work in an international team- an integrative and cooperative personality with excellent communicative and social skills- fluent proficiency in English – written and oral.Salary Benefits: We offer you in accordance with the Collective Labour Agreement for Dutch Universities: - a salary of € 2,770 (salary scale PhD candidates) gross per month in the first year, up to a maximum of € 3,539 gross per month in the fourth and final year, based on a full-time position- a holiday allowance of 8% gross annual income an 8.3% year-end bonus- a temporary position of one year with the option of renewal for another three years; prolongation of the contract is contingent on sufficient progress in the first year to indicate that you will successfully complete your PhD thesis within the next three years. A PhD training programme is part of the agreement.The preferred starting date is between June 1st and October 1st 2024.Work Hours: 38 hours per weekAddress: Broerstraat 5

The research area of Software-intensive systems includes any system where software influences the design, construction, deployment, operation and evolution of the system as a whole. This includes systems of systems, mobile applications, embedded systems, product lines, business processes, scientific computations and even whole enterprises, including systems processing huge amounts of data for AI and other data- and compute-intensive applications. The area draws on a wide variety of scientific fields such as software and systems engineering, information systems, theoretical computer science and distributed systems.Therefore, the expected candidate profile is in the area of Software-Intensive Systems and may fit any or a combination of the following research fields in terms of methodologies and expertise: Software Engineering, Theoretical Computer Science, Information Systems and Distributed Systems. We offer you a full-time position and excellent career opportunities in our faculty’s career system Career Paths in Science and Engineering, including the perspective to get a permanent appointment (tenure) in 1-3 years and become Full Professor in approximately 10 years. As Assistant Professor, you will:- set up and develop your own research line and research group- supervise PhD students- acquire external funding- promote the societal relevance of your research- teach in and contribute to the development of the degree programs of the School of Science and Engineering, especially courses with computing science content- contribute to the organization of the faculty, for example by participating in working groups and committees, in the domains of teaching, research and management.At the stage of Assistant Professor 60% of your time is for research, 30% for teaching activities and 10% for organizational tasks.For in-depth information regarding this position, including potential embedding in the Bernoulli Institute, applicants are strongly encouraged to consult the profile report, https://www.rug.nl/fse/meet-the-faculty/vacatures/vacatures/structuurrap...OrganizationThe University of Groningen is a research university with a global outlook, deeply rooted in Groningen, City of Talent. Groningen is the lively capital of the Northern Netherlands with a high quality of life and affordable living conditions.The Faculty of Science and Engineering (FSE) is the largest faculty within the University. We offer first-rate education and research in a wide range of science and engineering disciplines, from classical disciplines such as mathematics, physics, chemistry, astronomy, computer science and mechanical engineering, to interdisciplinary fields such as artificial intelligence, pharmacy and nanoscience. Our community has an open and informal character with students and staff from around the world.The position we offer will be embedded within the Bernoulli Institute for Mathematics, Computer Science and Artificial Intelligence, in the Computer Science Department. The specific research group in which the position will be embedded depends on the profile of the candidate and will be one of: Software Engineering, Fundamental Computing, Information Systems and Distributed Systems. The Bernoulli Institute is one of the leading institutes in Mathematics, Computer Science and Artificial Intelligence. It is a vibrant community with an international outlook, that fosters talent in all its research areas and disciplines, and is active in pure and applied science and (multi)disciplinary research and teaching.Requirements: We encourage you to apply if you have:- a PhD degree in computer science or a related field- at least two years of postdoctoral experience, preferably in a different country than where you received your PhD (can be compensated for after the appointment via extended research visits abroad)- a strong international research network- excellent research qualities, as shown by a publication record in international peer-reviewed journals and proceedings of renowned conferences- a good track record in teaching, appropriate to your career stage- demonstrable organizational competences- cross-cultural sensitivity- good command of spoken and written English.And you are: - a team player with good communication skills- able to acquire substantial research grants from external sources- willing to obtain a University Teaching Qualification (Dutch: BKO) within three years- able to speak the Dutch language or motivated to speak it within five years.Salary Benefits: The Faculty of Science and Engineering of the University of Groningen was the first on the European mainland to introduce a tenure track career policy, 20 years ago, and with significant success. We have attracted great talents that have contributed strongly to the worldwide leading position of our faculty’s ten research institutes. Our career system has helped our staff members to develop highly successful and rewarding academic careers. The latest version of this system, ‘Career Paths in Science and Engineering’, offers:- diverse career paths with a focus on research, education or impact- dynamic career paths, in which staff members can switch focus in the course of their career- the promotion to Assistant Professor level 1, in combination with a permanent contract, already after 1 - 3 years - a perspective for promotion to Associate Professor after 5 years, while the assessment for promotion to Full Professor can take place after another 5 years- significant freedom for staff members whether and when to apply for promotion.For more information about Career Paths in Science and Engineering, see: https://www.rug.nl/fse/meet-the-faculty/vacatures/vacatures/careerpaths/. Please consider the career path with a focus on research for the criteria for tenure and for promotion to more senior positions.As starting conditions, we offer a salary, depending on qualifications and work experience, from € 4,332 (salary scale 11) up to a maximum of € 6,737 gross per month (salary scale 12, depending on your career stage) for a full-time position as Assistant Professor. Additionally, we offer: - a holiday allowance and an end-of-year bonus of respectively 8% and 8.3% of your yearly salary- a pension scheme- maternity and parental leave- the possibility to work part-time (0.9 FTE or 0.8 FTE)- a mentor programme and a broad range of opportunities for personal development- dual career support for partners of new faculty members moving to Groningen.Consider our website for more information about the working conditions at the University of Groningen: https://www.rug.nl/about-ug/work-with-us/Work Hours: 38 hours per weekAddress: Broerstraat 5

We are looking to fill a two-year postdoctoral researcher position as a part of the Northern Netherlands Partnership (SNN) funded project through DigiAgro3 2024. The main goal of the post-doc project will be to develop machine learning models capable of robustly classifying images of agricultural crops based on markers for health state of the crop and deploying those models on a variety of low-power edge devices. The goal of the project is to enable precision farming practices, with a focus on sustainable and robust methods.We are looking for a highly motivated and independent Postdoctoral candidate with a background in mathematics, machine learning, and/or embedded devices, who is excited to work in an interdisciplinary environment. During your Post-doc, you will work together with our vibrant and interdisciplinary team, which consists of enthusiastic PhD students, Post-docs, and industry partners with backgrounds in machine learning, robotics, sensor technology, embedded devices, as well as agriculture and plant physiology.Job descriptionThe position is intended for two years with a start date as early as possible, before the end of June 2024. The postdoctoral candidate will conduct research in the field of Machine Learning, Image Analysis, Pattern Recognition, and Embedded AI. The candidate is expected to (i) conduct research related to dataset acquisition of plant images using a variety of camera setups including RGB, RGBI, multispectral, and hyperspectral cameras, (ii) investigate the relevance of each data modality, (iii) develop methods capable of classifying images containing healthy and stressed crops, (iv) adjust the models for deployment on a variety of edge devices, (v) and evaluate the performance of final deployments. The project requires interacting with a large consortium of academic and industrial partners and culminates by demonstrating the final product usable by our industrial partners. This setup provides the opportunity for an impactful and highly dynamic postdoctoral research experience leading to publication of academic research articles while working on an industry-relevant problem of high societal relevance.OrganisationSince its foundation in 1614, the University of Groningen has enjoyed an international reputation as a dynamic and innovative center of higher education offering high-quality teaching and research. Balanced study and career paths in a wide variety of disciplines encourage currently more than 34,000 students and researchers to develop their own individual talents. Belonging to the best research universities in Europe and the top 100 universities in the world (see our ranking: https://www.rug.nl/about-ug/profile/facts-and-figures/position-internati..., the University of Groningen is truly an international place of knowledge. Within the Faculty of Science and Engineering (FSE), the Engineering and Technology institute Groningen (ENTEG) conducts engineering science research and covers a broad area of mechanical engineering, electronic materials and MEMS, nanotechnology, control engineering, and robotics.This current postdoctoral project is a collaborative project between the Discrete Technology and Production Automation (DTPA) group, hosting Dr. Bahar Haghighat, and the Intelligent Systems Group, headed by Prof. Dr. Kerstin Bunte and hosting Dr. Michael Wilkinson. The Embedded AI/ML research thrust within DTPA research group led by Dr. Bahar Haghighat focuses on the development of embedded machine learning solutions that can be deployed on low-power low-memory embedded devices. Requirements: - have a PhD degree in Mathematics, Computer Science, Electrical Engineering, or another related field with strong mathematical training- excellent research qualities, as evidenced by a publication record in international peer-reviewed journals and renowned conferences, and a relevant international network- a dynamic, respectful, and pioneering professional attitude- ability to work independently and with colleagues- strong problem-solving ability- strong cross-cultural sensitivity and strong communication skills- able to communicate and teach in English. Knowledge of Dutch is an advantage but not obligatory.Salary Benefits: We offer you in accordance with the Collective Labour Agreement for Dutch Universities:- a salary from a minimum of € 3,877 gross per month up to a maximum of € 5,090 gross per month (salary scale 10) based on a full-time position and dependent on qualification and work experience- a holiday allowance of 8% gross annual income- an 8.3% end-of-the-year allowance- a position is available for 1 year with a possibility of extension.Work Hours: 38 hours per weekAddress: Broerstraat 5

Are you enthusiastic about enzymes and tailoring them for applications in synthetic organic chemistry? We are looking for a highly motivated and enthusiastic PhD student with strong backgrounds in chemistry, biochemistry, biotechnology or closely related fields to join the research group of Dr Sandy Schmidt, (http://schmidt-researchgroup.com) at the Department of Chemical and Pharmaceutical Biology (https://www.rug.nl/research/grip/cpb/) within the Groningen Research Institute of Pharmacy (GRIP). The position is funded for four years by the recently awarded ERC Starting grant ‘ReCNNSTRCT’.Biocatalysis uses enzymes to replace traditional catalysts. This technology has already established sustainable enzymatic approaches across various industrial sectors and led to economic and environmental benefits. Despite the growing impact of biocatalysis in industrial chemistry, the full potential of this technology is yet to be unlocked. Important current limitations are the following: i) only a limited set of chemical reactions is amenable to biocatalysis; and ii) the unique enzymology encoded in the genome of organisms is yet only minimally explored.In this context, we are interested in decoding novel reaction chemistries from the underexploited family of N-N bond-forming enzymes (NNZYMES), while tackling reactions that are difficult to realize by traditional chemical approaches and currently not feasible by enzyme catalysis. With this, we intend to build important molecules such as precursors for pharmaceuticals. A particular focus thereby lies on enzymes from natural product biosynthetic gene clusters that catalyze unique chemical reactions, but are tremendously underexplored as sustainable biocatalysts in the chemical industry. Although their native reactions have recently been investigated, the lack of knowledge on how these enzymes perform challenging reactions hinders a systematical exploration of their reactivity toward non-natural substrates and transformations.To fill this knowledge gap, in this PhD project we will extend the toolbox of NNZYMES as novel biocatalysts to access various N-N bond-containing compounds. In the laboratory, we thereby combine bioinformatic analysis with enzyme biochemistry, organic chemistry, instrumental analysis, and protein engineering to elucidate diverse N-N bond-forming reaction chemistries.The research group of Dr. Schmidt is embedded in the Chemical and Pharmaceutical Biology unit at the Groningen Research Institute of Pharmacy, which provides an inspiring, interdisciplinary and collaborative research environment.Founded in 1614, the University of Groningen enjoys an international reputation as a dynamic and innovative center of higher education offering high-quality teaching and research. Flexible study programmes and academic career opportunities in a wide variety of disciplines encourage the 36,000 students and researchers alike to develop their own individual talents. As one of the best research universities in Europe, the University of Groningen has joined forces with other top universities and networks worldwide to become a truly global center of knowledge. The Faculty of Science and Engineering (FSE) is the largest faculty within the University. We offer first-rate education and research in a wide range of science and engineering disciplines. Our community has an open and informal character with students and staff from around the world.The research group Chemical and Pharmaceutical Biology (CPB) within GRIP consists of an enthusiastic group of researchers from different parts of the world. The scientific staff currently includes two full professors, one associate professor, and four assistant professors. In addition, five postdocs, four technicians and >25 PhD students are members of the research group. A strong research focus of CPB is on the creation of superior biocatalysts for the sustainable production of pharmaceuticals.Requirements: The ideal candidate for this project is an experimental chemist, with affinity or interest in biocatalysis, bioinformatics and protein engineering.Your profile includes:- a Master degree in chemistry, biotechnology, biochemistry or related field- ability to work in an international team- inter- and multidisciplinary thinking- high motivation- an integrative and cooperative personality with excellent communication and social skills- fluency in English – written and oral.Salary Benefits: We offer you, in accordance with the Collective Labour Agreement for Dutch Universities:- a salary of € 2,770 gross per month in the first year, up to a maximum of € 3,539 gross per month in the fourth and final year- a full-time position (1.0 FTE)- a holiday allowance of 8% of gross annual income- an 8.3% end-of-the-year allowance.The successful candidate will first be offered a temporary position of one year with the option of renewal for another three years. Prolongation of the contract is contingent on sufficient progress in the first year to indicate that successful completion of the PhD thesis within the next three years is to be expected. A PhD training program is part of the agreement and the successful candidate will be enrolled in the Graduate School of Science and Engineering.The conditions of employment: https://www.rug.nl/about-us/work-with-us/The planned starting date is June/July 2024, however, there is some flexibility in the starting date.Work Hours: 38 hours per weekAddress: Broerstraat 5

We are looking for an Assistant Professor to strengthen our position in the field of Computer-Aided Drug Design (CADD). This discipline plays an increasingly important role in the process of drug discovery and aims to reduce the costs in both time and resources in the drug discovery process, also facilitating higher success rates in subsequent clinical trials.Whether your expertise lies in structure- and ligand-based drug design, de novo and fragment-based drug design, molecular dynamics, or Quantum Mechanics/Molecular Mechanics, or you are actively working on incorporating machine learning/AI into your computer-aided drug design approaches, we would be very interested in hearing from you.We offer you a full-time position and excellent career opportunities in our faculty’s career system Career Paths in Science and Engineering, including the perspective to get a permanent appointment (tenure) in 1-3 years and become Full Professor in approximately 10 years.As Assistant Professor with a focus on research you will:• set up and develop your own research line and research group in the field described above• supervise PhD students• acquire external funding• promote the societal relevance of your research• teach courses within the bachelor and/or master degree programs Pharmacy and Medical Pharmaceutical Sciences, and contribute to the further development of these programmes• contribute to the organization of the faculty, for example by participating in working groups and committees.At the stage of Assistant Professor, 60% of your time is for research, 30% for teaching activities and 10% for organizational tasks.OrganisationThe University of Groningen is a research university with a global outlook, deeply rooted in Groningen, City of Talent. Groningen is the lively capital of the Northern Netherlands with a high quality of life and affordable living conditions. The University has 32.000 students in BSc and MSc programmes, 4400 PhD students, and 4600 staff members. Our students and staff come from all around the world.Quality has been our top priority for over four hundred years, and with success: the University is currently in or around the top 100 on several influential ranking lists. The Faculty of Science and Engineering (FSE) is the largest faculty within the University. We offer first-rate education and research in a wide range of science and engineering disciplines, from classical disciplines such as mathematics, astronomy and mechanical engineering, to interdisciplinary fields such as artificial intelligence, pharmacy and nanoscience. At FSE, education and research are strongly intertwined, and we value a strong disciplinary basis for our students. Our programmes in science and engineering, while diverse, share a common view on best practices for research-driven, international education. We are proud of the open, inclusive, and informal character of our community.The position we offer will be embedded in the research group Medicinal Chemistry, Photopharmacology and Imaging (https://www.rug.nl/research/medicinal-chemistry-photopharmacology-and-im...), which was recently created within GRIP, see also the Szymanski lab (https://szymanski-lab.nl/Index.html) website for more information. Although GRIP is positioned within the Faculty of Science and Engineering, it is physically located within the University Medical Centre Groningen (UMCG) of the Faculty of Medical Sciences - hence, in ideal proximity to benefit from collaborations between the two faculties. Pharmaceutical research within GRIP is highly multidisciplinary and bridges the clinical and biomedical sciences on the one hand, and chemistry, mathematics (statistics) and physics on the other. The interaction between the pharmaceutical sciences and these fundamental and clinical sciences offers excellent opportunities for ground-breaking research.Requirements: We encourage you to apply if you have:• a PhD degree in (bio)chemical, (bio)medical or pharmaceutical sciences, or Machine Learning/Artificial Intelligence, with a strong background in computer-aided drug design, both as a user and as a developer of new computational approaches• excellent research qualities, as shown by a publication record in international peer-reviewed journals and proceedings of renowned conferences• a proven ability and desire to collaborate with colleagues in the related fields, including synthetic chemistry, medicinal chemistry, pharmacology, and pre-clinical studies• a great affinity with and a good track record in teaching, appropriate for the career stage• preferably at least two years of postdoctoral experience and preferably research experience outside of The Netherlands• a relevant international network• the potential to acquire substantial research grants from external sources• demonstrable communicative and organisational competences• the ambition and the potential to develop academically• the ability to work well with others in international and diverse teams• good command of spoken and written English.Furthermore, we expect all new staff members to either have a University Teaching Qualification (Dutch: Basiskwalificatie Onderwijs) or obtain it within 3 years and, if they do not already speak it, to learn the Dutch language within at most five years.Salary Benefits: The Faculty of Science and Engineering of the University of Groningen was the first on the European mainland to introduce a tenure track career policy, 20 years ago, and with significant success. We have attracted great talents that have contributed strongly to the worldwide leading position of our faculty’s ten research institutes. Our career system has helped our staff members to develop highly successful and rewarding academic careers. The latest version of this system, ‘Career Paths in Science and Engineering’, offers:• diverse career paths with a focus on research, education or impact• dynamic career paths, in which staff members can switch focus in the course of their career• the promotion to Assistant Professor level 1, in combination with a permanent contract, already after 1 – 3 years• promotion to Associate Professor after 5 years, and promotion to Full Professor after another 5 years, if the corresponding criteria are met• significant freedom for staff members whether and when to apply for promotion.For more information about Career Paths in Science and Engineering, see: http://www.rugfriso.nl/fse/cpse Please consider the career path with a focus on research for the criteria for tenure and for promotion to more senior positions.As starting conditions, we offer in accordance with the Collective Labour Agreement for Dutch Universities a salary, depending on qualifications and work experience, from € 4,332 (salary scale 11) up to a maximum of € 6,737 gross per month (salary scale 12, depending on your career stage) for a full-time position as Assistant Professor. Additionally, we offer:• a holiday allowance and an end-of-year bonus of respectively 8% and 8.3% of your yearly salary• a pension scheme• maternity and parental leave• the possibility to work part-time (0.9 FTE or 0.8 FTE)• a mentor programme and a broad range of opportunities for personal development• dual career support for partners of new faculty members moving to Groningen.Consider our website for more information about the working conditions at the University of Groningen: https://www.rug.nl/about-ug/work-with-us/Work Hours: 38 hours per weekAddress: Broerstraat 5

ProjectmanagerGroningen/HengeloEen rijke geschiedenis in toekomst creërenWij zijn Bilfinger Tebodin. Onze industriële klanten staan voor de uitdaging om te verduurzamen door het zoeken naar alternatieven energiebronnen, het sluiten van de grondstoffencyclus en het minimaliseren van impact op de omgeving. Hoe vertaalt dit zich in concrete oplossingen? Wij zorgen ervoor dat onze klanten uit de industrie hun uitdagingen kunnen waarmaken. Door innovatieve technieken en het gebruik van hedendaagse mogelijkheden van digitalisering maken wij de ambities van onze klanten waar. Al sinds de wederopbouw na de oorlogsjaren in 1945, zijn we hèt toonaangevende ingenieurs: en adviesbureau voor het creëren van een toekomstbestendige industrie.Onze engineers en consultants lopen voorop in het realiseren van industriële investeringsprojecten. Onze toonaangevende klanten zijn actief in zeer uiteenlopende industrieën zoals de olie en gas, voedingsmiddelenindustrie, chemie en farmacie. Ze vertrouwen hun investeringsprojecten toe aan een team dat voorop loopt in het begrijpen van hun business en kan bouwen op technische expertise en jarenlange ervaring. Voor deze klanten leveren wij consultancy, engineering, project management, inkoop en constructie management services, kortom alles wat de klant nodig heeft om hun project succesvol te makenLoop jij ook voorop in jouw vakgebied Project Management? Wil jij graag werken aan projecten met een grote diversiteit aan klanten om daarmee de industrie toekomstbestendig te maken? Begrijp je snel de complexe vraagstukken van onze klanten en ben jij een uitstekende gesprekspartner voor onze klanten? Werk je graag in een informele cultuur met multidisciplinaire teams samen om interessante projecten te realiseren? Wil je werken in een organisatie waarin je snel kan ontwikkelen door opleidingen, coaching en regelmatig nieuwe uitdagingen? Dan passen wij bij jouWat houdt deze functie in?:Je werkt binnen de afdeling Projecten (met als standplaats Hengelo of Groningen) voor onze eindklanten op kantoor of op locatie. Je bent verantwoordelijk voor het projectmanagement voor alle fases binnen een project (TIC : ca. 25M EUR) in de voedingsmiddelen, farmaceutische, chemische industrie en bent bezig met projecten binnen de energietransitie en werkt aan duurzaamheidsvraagstukken met onze klanten. In uitvoerende fase werk je nauw samen met constructiemanagement.:Ook ben je eindverantwoordelijk voor het aansturen van een multidisciplinaire engineering team, gebruik makende van je soft skills en focus op interdisciplinair en interface management.:Tevens ben je in controle wat betreft budget, scope, planning en inkoop door het uitvoeren van met name risicomanagement, change management, stakeholder management en contractmanagement. Je bewaakt continue de kwaliteit van het geleverde werk.:Naast het leiden van het project maak je gebruik van jouw eigen technische kennis om zo de behoefte van het project aan te vullen en daar waar nodig schakel je vakdisciplines in.:De functie is snel en veelzijdig. Je balanceert tussen meerdere projecten en klanten.:Je hebt regelmatig overleg met de opdrachtgever en je zorgt voor voortgangsrapportages en een vlotte en correcte communicatie.:Je bent verantwoordelijk voor de administratie en facturatie van projecten tot aan de definitieve oplevering. Wat heb jij te bieden?:Een afgeronde technische of bedrijfskundige hbo of wo opleiding.:Je hebt minimaal 5jaar ervaring als Projectmanager in multidisciplinaire projecten.:Plus voldoende technische achtergrond om projecten aan te sturen en te begeleiden.:Je bent iemand die goed kan organiseren om jouw projecten te kunnen overzien.:Ook ben je proactief en los je problemen binnen de projecten op.:Je kunt goed samenwerken en bent resultaatgericht.:Daarnaast ben je in staat om prioriteiten af te wegen en je aan te

We have an opening for an Assistant Professor who is interested to start a career that focuses on education and who can strengthen our teaching and research in the field of (applied/pure) mathematics. The position is opened to teach mathematics to non-maths students (in science and engineering) as well as to conduct research in mathematics. Excellence in teaching and research and a commitment to interdisciplinary teaching are expected. The teaching duties will normally consist of one course (5 ECTS) each quarter as well as supervising BSc and MSc student research projects. The courses mainly concern calculus, linear algebra, statistics, numerical mathematics. Innovation of interdisciplinary mathematics education is an essential part of the tasks. This includes improving students’ conceptual and contextual understanding of mathematics as well as promoting student engagement and learning. We particularly welcome applications in the research areas Probability and Statistics, Systems Control & Optimization or Computational and Numerical Mathematics; applications in the areas Algebra or Dynamical Systems, Geometry & Mathematical Physics are also possible (see Organization for more details). Within the framework of these research areas, you can develop your own research line and/or contribute to existing research lines. Research activities include publishing in leading journals, (co-)supervising of PhD-students, maintaining and/or developing research collaborations and (co-)writing grant proposals.Because of our commitment to promoting diversity in the department, we have a preference for female candidates.We offer you a full-time position and excellent career opportunities in our faculty’s career system Career Paths in Science and Engineering, including the perspective to get a permanent appointment (tenure) in 1-3 years and become Full Professor in approximately 10 years.As Assistant Professor with a focus on education you will● teach mathematics in degree programmes in science and engineering● play a significant role in curriculum development and teaching innovation the development of education at the Faculty of Science and Engineering, both at the course and the programme level● contribute to research lines in the research group and/or possibly develop your own research line● contribute to the supervision of PhD students in the research group● contribute to the organization of the faculty, for example by participating in working groups and committees, especially in the domain of education.At the stage of Assistant Professor, 60% of your time is dedicated to teaching and education development, 30% to research and 10% to organizational tasks.OrganisationThe University of Groningen is a research university with a global outlook, deeply rooted in Groningen, City of Talent. Groningen is the lively capital of the Northern Netherlands with a high quality of life and affordable living conditions. The University has 34.000 students in BSc and MSc programmes, 4.400 PhD students, and 4.600 staff members. Our students and staff come from all around the world.Quality has been our top priority for over four hundred years, and with success: the University is currently in or around the top 100 on several influential ranking lists. The Faculty of Science and Engineering (FSE) is the largest faculty within the University. We offer first-rate education and research in a wide range of science and engineering disciplines, from classical disciplines such as mathematics, astronomy and mechanical engineering, to interdisciplinary fields such as artificial intelligence, pharmacy and nanoscience [change fields if desirable]. At FSE, education and research are strongly intertwined, and we value a strong disciplinary basis for our students. Our programmes in science and engineering, while diverse, share a common view on best practices for research-driven, international education. We are proud of the open, inclusive, and informal character of our community.The position we offer will be embedded in one of the mathematics-oriented research groups of the Bernoulli Institute, depending on the actual research profile of the selected candidate. The Bernoulli Institute (BI) for Mathematics, Computer Science and Artificial Intelligence is a vibrant community with an international outlook, which fosters talent in all its research areas and disciplines and is active in pure and applied science, and (multi)disciplinary research and teaching. BI strives at maintaining a balanced mix of fundamental and applied research. It comprises 15 basic research units, of which 5 are mathematics oriented. The five mathematics-oriented basic units are: 1. Algebra, 2. Computational & Numerical Mathematics, 3. Dynamical Systems, Geometry & Mathematical Physics, 4. Probability & Statistics, and 5. Systems, Control & Optimization. We aim for an equal distribution of assistant professors with an education profile over the mathematics-oriented base units. Considering the current distribution, candidates for basic units 2, 4 and 5 are given preference if candidates have equivalent qualities. Candidates are expected to keep an open eye for research connections to other groups within BI. More information about BI can be found on our website https://www.rug.nl/research/bernoulli/Requirements: We seek candidates with the following characteristics● a PhD degree in mathematics or a related field● a passion for education and excellent teaching qualities, based on a clear vision on education● the ability to inspire students and colleagues● a good track record in research, as shown by publications in international peer-reviewed journals and proceedings of renowned conferences and a research statement● preferably at least two years of relevant work experience after your PhD● demonstrable communicative and organizational competences● the ambition and the potential to develop academically● the ability to work well with others in international and diverse teams● good command of spoken and written English.Furthermore, we expect all new staff members to either have a University Teaching Qualification (Dutch: Basiskwalificatie Onderwijs) or obtain it within 3 years and, if they do not already speak it, to learn the Dutch language within at most five years.Salary Benefits: The Faculty of Science and Engineering of the University of Groningen was the first on the European mainland to introduce a tenure track career policy, 20 years ago, and with significant success. We have attracted great talents that have contributed strongly to the worldwide leading position of our faculty’s ten research institutes. Our career system has helped our staff members to develop highly successful and rewarding academic careers. The latest version of this system, ‘Career Paths in Science and Engineering’, offers● diverse career paths with a focus on research, education or impact● dynamic career paths, in which staff members can switch focus in the course of their career● promotion to Assistant Professor level 1, in combination with a permanent contract, already after 1 - 3 years, provided the relevant criteria are met● promotion to Associate Professor after 5 years, and promotion to Full Professor after another 5 years, if the corresponding criteria are met● significant freedom for staff members whether and when to apply for promotion.For more information about Career Paths in Science and Engineering, see: http://www.rug.nl/fse/cpse Please consider the career path with a focus on education for the criteria for tenure and for promotion to more senior positions.As starting conditions, we offer a salary, depending on qualifications and work experience, from € 4,332 (salary scale 11) up to a maximum of € 6,737 gross per month (salary scale 12, depending on your career stage) for a full-time position as Assistant Professor. Additionally, we offer● a holiday allowance and an end-of-year bonus of respectively 8% and 8.3% of your yearly salary● a pension scheme● maternity and parental leave● the possibility of working part-time (0.9 FTE or 0.8 FTE)● a mentor programme and a broad range of opportunities for personal development● dual career support for partners of new faculty members moving to Groningen.Consider our website for more information about the working conditions at the University of Groningen: https://www.rug.nl/about-ug/work-with-usWork Hours: 38 hours per weekAddress: Broerstraat 5

Randomness and random shapes can be found everywhere around us, for example the shape of a tree is influenced by random interactions both between and within its cells, and random external influences. This random growth causes trees in nature to have self-similar, fractal-like properties. Underlying random growth also makes our backyard oak look remarkably similar to other structures in nature and systems of human design, such as the shape of river systems; the circulatory system in animals; and the connectivity structure of the internet and digital social networks. Broccolis looking like trees is a consequence of a universality principle in random structures: the precise random dynamics of cell growth in the two organisms is different, but those differences have a negligible effect on the overall structure.The goal of this PhD project is to examine universality in random trees and graphs. (Morally, you will rigorously prove what it takes to look like a broccoli.) The focus will lie on directed graphs (in which edges have directions) and dynamical trees and graphs (in which the connectivity structure evolves over time). This research requires the PhD candidate to develop new combinatorial sampling methods, and to use techniques from (stochastic) analysis to study limiting properties. The PhD candidate will acquire skills that are broadly applicable in combinatorics and analysis, and in discrete and continuous probability theory. The objective of the temporary position is the production of a number of research articles in peer-reviewed scientific journals and conference proceedings, which together will form the basis of a thesis leading to a PhD degree (Dr) at the University of Groningen. The position comes with a light teaching duty. The candidate will become a member of the Probability and Statistics Group of the Mathematics Department and will work under the supervision of Serte Donderwinkel.OrganisationFounded in 1614, the University of Groningen enjoys an international reputation as a dynamic and innovative institution of higher education offering high-quality teaching and research. Flexible study programmes and academic career opportunities in a wide variety of disciplines encourage the 34,000 students and researchers alike to develop their own individual talents. As one of the best research universities in Europe, the University of Groningen has joined forces with other top universities and networks worldwide to become a truly global center of knowledge.Requirements: The successful candidate should- have a Master’s degree or equivalent in mathematics or another relevant field with sufficient mathematical content; preferably with a focus on combinatorics or probability theory- have good English language and communication skills.Salary Benefits: We offer you, following the Collective Labour Agreement for Dutch Universities- a salary of € 2,770 gross per month in the first year, up to a maximum of € 3,539 gross per month in the fourth and final year for a full-time working week- a holiday allowance of 8% gross annual income and an 8.3% year-end bonus- a full-time position (1.0 FTE).The successful candidate will first be offered a temporary position of one year with the option of renewal for another three years. Prolongation of the contract is contingent on sufficient progress in the first year to indicate that a successful completion of the PhD thesis within the next three years is to be expected. A PhD training programme is part of the agreement and the successful candidate will be enrolled in the Graduate School of Science and Engineering.Preferred starting date: September 1 (or in consultation with the candidate)Work Hours: 38 hours per weekAddress: Broerstraat 5

Without biological membranes, there would be no life as we know it. Transport of molecules and information across these membranes is carried out by integral membrane protein channels, receptors, pumps and transporters. Living cells maintain chemical gradients and electrical potential differences across their membranes using proteins that represent the majority of all current drug targets. Therefore, membrane proteins have been the focus of intense efforts to obtain high resolution macromolecular structure information. However, the current lack of experimental methods to carry out time-resolved structural studies of membrane proteins at physiological temperatures and under physiological gradients leaves a gigantic blind spot is our mechanistic understanding. This project is a part of an ERC-funded consortium that will address this challenge by bringing together complementary expertise in membrane protein biology, time-resolved structural studies, photochemistry and nano fabrication methods. The role of the PhD working in this position will be to design, synthesize and evaluate new light-activated molecules to deliver protein transport substrates with unprecedented efficiency. Within this team, the PhD student will be supported, among others, by a dedicated postdoc researcher with expertise in quantum chemistry for guiding the development of light-activated molecules.OrganizationThe vacancy is within the newly formed Department of Medicinal Chemistry, Photopharmacology and Imaging at the Groningen Research Institute of Pharmacy, Faculty of Science and Engineering, University of Groningen. The ERC-funded (ERC Synergy GRAIL) project aims at providing molecular basis for the instant, photochemical release of ligands for proteins studied in unprecedented level of structural dynamics using equipment developed by the GRAIL consortium.The University of Groningen (founded in 1614) has a long tradition of academic excellence, being one of the oldest research universities in Europe. The University is currently in or around the top 100 on several influential ranking lists. Currently approximately 34,000 students are enrolled and about 1,500 PhD students work on their theses. The city of Groningen is a historic town and among the ten biggest cities in The Netherlands. It is a vibrant student town with a direct train connection to Schiphol Airport near Amsterdam.The Groningen Research Institute of Pharmacy (GRIP) is part of the Faculty of Science and Engineering (FSE) of the University of Groningen and collaborates closely with the University Medical Center Groningen (UMCG). The pharmaceutical and medical research within GRIP and the UMCG is very multidisciplinary. This project aims to develop light-activation processes for the emerging field of time-resolved structural biology, fitting perfectly into the fundamental and applied work performed in the Department of Medicinal Chemistry, Photopharmacology and Imaging at GRIP. Requirements: We are looking for an enthusiastic and talented PhD candidate with- a M.Sc. degree in (Synthetic) Organic Chemistry- research experience in the field of photochemistry, photocleavable protecting groups and/or photopharmacology will be seen as a strong asset- capacity to think analytically and creatively- high motivation- ability to work in an international team and collaborate with several research centres in Europe in a streamlined and professional way- an integrative and cooperative personality with excellent communicative and social skills- fluent proficiency in English – written and oral.Applicants whose first language is not English must submit evidence of competency in English, please see University of Groningen’s English Language Requirements for details.Salary Benefits: We offer you in accordance with the Collective Labour Agreement for Dutch Universities- a salary of € 2,770 (salary scale PhD candidates) gross per month in the first year, up to a maximum of € 3,539 gross per month in the fourth and final year, based on a full-time position- a holiday allowance of 8% gross annual income an 8.3% year-end bonus- a temporary position of one year with the option of renewal for another three years; prolongation of the contract is contingent on sufficient progress in the first year to indicate that you will successfully complete your PhD thesis within the next three years. A PhD training programme is part of the agreement.The preferred starting date is between September 1st and October 1st 2024.Work Hours: 38 hours per weekAddress: Broerstraat 5

Without biological membranes, there would be no life as we know it. Transport of molecules and information across these membranes is carried out by integral membrane protein channels, receptors, pumps and transporters. Living cells maintain chemical gradients and electrical potential differences across their membranes using proteins that represent the majority of all current drug targets. Therefore, membrane proteins have been the focus of intense efforts to obtain high resolution macromolecular structure information. However, the current lack of experimental methods to carry out time-resolved structural studies of membrane proteins at physiological temperatures and under physiological gradients leaves a gigantic blind spot is our mechanistic understanding.This project is a part of an ERC-funded consortium that will address this challenge by bringing together complementary expertise in membrane protein biology, time-resolved structural studies, photochemistry and nano fabrication methods. The role of the postdoctoral researcher working in this position will be to provide computational support to the development of new light-activated molecules to deliver protein transport substrates with unprecedented efficiency. Within this team, the postdoctoral researcher will support a PhD student responsible for synthesis and photochemical evaluation of the designed molecules.OrganizationThe vacancy is within the newly formed Department of Medicinal Chemistry, Photopharmacology and Imaging at the Groningen Research Institute of Pharmacy, Faculty of Science and Engineering, University of Groningen. The ERC-funded (ERC Synergy GRAIL) project aims at providing molecular basis for the instant, photochemical release of ligands for proteins studied in unprecedented level of structural dynamics using equipment developed by the GRAIL consortium.The University of Groningen (founded in 1614) has a long tradition of academic excellence, being one of the oldest research universities in Europe. The University is currently in or around the top 100 on several influential ranking lists. Currently approximately 30,000 students are enrolled and about 1,500 PhD students work on their theses. The city of Groningen is a historic town and among the ten biggest cities in The Netherlands. It is a vibrant student town with a direct train connection to Schiphol Airport near Amsterdam.The Groningen Research Institute of Pharmacy (GRIP) is part of the Faculty of Science and Engineering (FSE) of the University of Groningen and collaborates closely with the University Medical Center Groningen (UMCG). The pharmaceutical and medical research within GRIP and the UMCG is very multidisciplinary. This project aims to develop light-activation processes for the emerging field of time-resolved structural biology, fitting perfectly into the fundamental and applied work performed in the Department of Medicinal Chemistry, Photopharmacology and Imaging at GRIP.Requirements: We are looking for candidates who meet the following requirements- a PhD degree in (computational) chemistry- knowledge and skills in photochemistry and QM methods for calculating the excited state properties of molecules (TD-DFT etc.)- a relevant publication record demonstrating your ability to publish international academic publications- the ability to communicate verbally and in written form in English- ability to work in an international team and collaborate with several research centres in Europe in a streamlined and professional way.Applicants whose first language is not English must submit evidence of competency in English, please see University of Groningen’s English Language Requirements for details.Salary Benefits: We offer you, in accordance with the Collective Labour Agreement for Dutch Universities- a salary of € 3,877 gross per month in the first year, up to a maximum of € 5,090 gross per month (salary scale 10) based on a full-time position and dependent on qualification and work experience- excellent secondary terms of employment- a fulltime position- a holiday allowance of 8% gross annual income and an 8.3% end-of-year bonus- participation in a pension scheme for employees- a personal budget of € 1,000 per year for additional training and career activities- a temporary appointment for a specified period of 12 months, with a possibility of extension.The preferred starting date is September 1st or October 1st 2024.Work Hours: 38 hours per weekAddress: Broerstraat 5

Von Willebrand Factor (VWF) plays a pivotal role in blood coagulation, with its secretion from Weibel-Palade bodies (WPBs) being essential for responding to vascular trauma. Dysfunctional WPB biogenesis and exocytosis are characteristic of bleeding disorders such as Von Willebrand disease. In this project, we aim to identify the organelle trafficking routes responsible for WPB formation and secretion.This project is a collaboration between the research groups of Dr. Ruben Bierings (Department of Hematology, Erasmus MC, Rotterdam) and Dr. Geert van den Bogaart (Department of Molecular Immunology, University of Groningen (UG)).Two PhD positions are available, one at each institute.The UG candidate will utilize newly developed microscopy methods, including Förster resonance energy transfer-fluorescence lifetime imaging (FRET-FLIM), to map SNARE protein trafficking to WPBs. Techniques include FRET-FLIM microscopy, mammalian cell culturing, CRISPR, and molecular cloning.The Erasmus MC candidate will conduct biochemical assays of WPB cargo secretion and optical assays of WPB exocytosis to determine changes in secretory competence and fusion mode due to altered SNARE sorting. Techniques include high content microscopy, proteomics, total internal reflection fluorescence (TIRF) microscopy, shRNA library screenings, and electron microscopy.The PhD candidates are expected to also spend research time at the other institute.Founded in 1614, the University of Groningen (http://www.rug.nl) enjoys an international reputation as a dynamic and innovative center of higher education offering high-quality teaching and research. Flexible study programmes and academic career opportunities in a wide variety of disciplines encourage the 36,000 students and researchers alike to develop their own individual talents. As one of the best research universities in Europe, the University of Groningen has joined forces with other top universities and networks worldwide to become a truly global center of knowledge.This is a collaborative project between the Department of Molecular Immunology at the Faculty of Science and Engineering (FSE; www.membranetrafficking.com), and the Department of Hematology at the Erasmus Medical Center in Rotterdam (https://www.hematologyrotterdam.nl/laboratory-research/ruben-bierings).Requirements: The successful applicant has:- a Master degree in one of the following expertise: molecular biology, biochemistry.- a good command of English (oral and written)- enthusiastic and a team player.- willing to spend research time in Rotterdam / Groningen- experience with mammalian cell biology and advanced microscopy approaches is an advantage.Salary Benefits: We offer stimulating scientific environment, access of state-of-the-art devices and techniques, and a beautiful and modern working environment. Employment possibilities will also become available at spinout company from the laboratory.We offer you in accordance with the Collective Labour Agreement for Dutch Universities:- a salary of € 2,770 gross per month in the first year, up to a maximum of € 3,539 gross per month in the fourth and final year- a full-time position (1.0 FTE)- a holiday allowance of 8% of gross annual income- an 8.3% end-of-the-year allowance- minimum of 29 holidays and additional 12 holidays in case of full-time employment.The successful candidate will first be offered a temporary position of one year with the option of renewal for another three years. Prolongation of the contract is contingent on sufficient progress in the first year to indicate that successful completion of the PhD thesis within the next three years is to be expected. A PhD training program is part of the agreement and the successful candidate will be enrolled in the Graduate School of Science and Engineering.The preferred starting date is as soon as possible.Work Hours: 38 hours per weekAddress: Broerstraat 5